Diabetic kidney disease (DKD), also called diabetic nephropathy, refers to CKD that is present in persons with diabetes and is defined as macroalbuminuria (urinary albumin-to-creatinine ratio [ACR] >30 mg/mmol), or microalbuminuria (ACR: 3–30 mg/mmol) associated with retinopathy and/or more than 10 years duration of type 1 diabetes mellitus3. The gene discussed is ALB; the disease is diabetic kidney disease.