CAMK2A and neuropathic pain: At the behavioral level, our findings suggest that the selective optogenetic inhibition of CaMKIIα-eNpHR3.0-expressing neurons is able to improve WM performance of rats with neuropathic pain when the photo-inhibition is applied throughout the whole delay-period at shorter WM challenges (3 s), and when the photo-inhibition is applied to the late phase of the delay-period at longer WM challenges (6 s).