There is a broad panel of known cytokines involved in tumor angiogenesis including vascular endothelial growth factor (VEGF), Angiopoietin 1 (Ang1), platelet-derived growth Factor A and B (PDGF-A, PDGF-B), the chemokine Interleukin 8 (IL-8) and basic fibroblast growth factor (bFGF)7–9. The gene discussed is VEGFA; the disease is neoplasm.