To investigate the clinical relevance of our findings, we examined the protein levels of Nogo-B, CD36, CEBPβ, and p-YAP by western blot analysis in 16 pairs of human NAFLD-associated HCCs without either viral or alcoholic hepatitis, and 12 pairs of HBV-positive HCC patients. This evidence concerns the gene CEBPB and hepatocellular carcinoma.