To explore the molecular mechanism, we analyzed the transcription factor ChIP-seq database and identified CCAAT/enhancer-binding protein β (CEBPβ), a downstream target of oxLDL reported in atherosclerosis, a chronic inflammatory disease and lipid metabolism disorder15, as a potential regulator of Nogo-B (Supplementary Fig. 2H). This evidence concerns the gene CEBPB and atherosclerosis.