To determine the ceRNA network between LINC02418 and MELK in CRC, we transfected CRC cells with si-LINC02418 1# and 2# and the results showed that the knockdown of LINC02418 also significantly reduced the MELK mRNA and protein levels in SW1116 and HT29 cells (Fig. 5a, b). This evidence concerns the gene MELK and colorectal carcinoma.