Bi WR et al. [18] proposed that bone morphogenetic protein-7 could induce down-regulation of 1α-SMA mRNA and up-regulation of E-cadherin mRNA, which could promote the transformation of EMT to mesenchymal-epithelial transition (MET) in rat hepatocyte, thereby reducing liver fibrosis. This evidence concerns the gene GDI1 and Hepatic fibrosis.