Cackowski et al. [36] demonstrated that MERTK, one of TAM family of receptor tyrosine kinases, being knockdown could induce a G0/G1 arrest in prostate cancer cells via increasing expression of NR2F1 and ratio of p38 to pERK1/2, which was reversed by p38 inhibitor. This evidence concerns the gene MERTK and Familial prostate cancer.