ALB and nutritional deficiency disease: The preliminary studies showed that, the decrease of albumin [37] and the increase of alpha-2 globulin [38] could be seen in the patients with pulmonary tuberculosis, which just reduced the albumin-globulin ratio, thereby affecting the body’s immune function, and possible mechanisms might be: (1) Malnutrition may impair the functions of antigen presenting cells [39] and inhibit glucose metabolism-dependent T cell activation [40, 41].