CYP2R1 and thyroid cancer: This is in agreement with Penna-Martinez et al. [24] who analyzed different SNPs within CYP2R1 (rs12794714 and rs10741657) and CYP24A1 (rs927650, rs2248137, rs2296241) and found no association of thyroid cancer with each individual SNP, even though certain haplotypes of CYP24A1 were associated with a higher risk.