Another study found no association between GSTP1 Ile105Val or Ala114Val genotype and an increased risk of multiple myeloma but suggested that polymorphic variation in GSTP1 are significant predictors of outcome following treatment with chemotherapeutic agents and may be a step in the development of more individualized treatment regimens for myeloma based on host genetic factors [121]. The gene discussed is GSTP1; the disease is AL amyloidosis.