As illustrated in Table 2, overall results of first and second TRUS biopsy showed that 24 (34%) of 71 patients with PSA <10 ng/mL, 15 (47%) of 32 patients with PSA 10–20 ng/mL, and 36 (84%) of 43 patients with PSA >20 ng/mL were positive for any cancer. Here, KLK3 is linked to cancer.