KLK3 and cancer: Clinically significant cancer with Gleason score 3 + 4 or higher was found in 15 of 71 (21%) patients with PSA <10 ng/mL, 12 of 32 (38%) patients with PSA 10–20 ng/mL, and 36 of 43 (84%) patients with PSA >20 ng/mL, while csPCa with Gleason score 4 + 3 or higher was found in 9 of 71 (13%) patients with PSA <10 ng/mL, 8 of 32 (25%) patients with PSA 10–20 ng/mL, and 31 of 43 (72%) patients with PSA >20 ng/mL.