Different regulation levels among pediatric astrocytoma grades were described for several proteins, including Calreticulin (CALR) and 14-3-3 protein epsilon (1433E) and for 22 miRNA, among which 12 were involved in the glycosaminoglycan biosynthesis, a pathway that was previously described in the invasion and progression of glioblastoma [51]. This evidence concerns the gene CALR and astrocytoma (excluding glioblastoma).