In a recently published pan-tissue, pan-cancer analysis of RNA-seq data specific to the seven APOBEC3 genes in 8951 tumors, 786 cancer cell lines and 6119 normal tissues, APOBEC3B consistently demonstrated its association with proliferative cells and processes, in contrast to other APOBEC3s, especially APOBEC3G and APOBEC3H, which were revealed as more immune cell related [9]. This evidence concerns the gene APOBEC3G and cancer.