LGALS3 and urinary bladder neoplasm: For instance, the poly N-acetyllactosamine, the polymers of LacNAc mediated binding of galectin-3 to MHC class I-related chain A (MICA) has been demonstrated to contribute to the survival of bladder tumor cells and prevent the NK-mediated killing of C2GnT-expressing bladder tumor cells (60, 61).