CYLD and lymphoma: As shown in Table 6, among the 299 genes analyzed, LIUS induced upregulation of 13 genes in lymphoma cells including BOK, CASP10, CYLD, DPP4, EZR, ATG3, ATG16L1, VAMP1, CXCL10, ANXA1, FPR1, PANX1, and TP53; and downregulated 12 genes such as HK2, CASP5, TLR7, MAP2K5, CD47, ATM, CDC25C, TTK, SRC, PDGFRA, ITGB1, and ITGB3.