As shown in Table 6, among the 299 genes analyzed, LIUS induced upregulation of 13 genes in lymphoma cells including BOK, CASP10, CYLD, DPP4, EZR, ATG3, ATG16L1, VAMP1, CXCL10, ANXA1, FPR1, PANX1, and TP53; and downregulated 12 genes such as HK2, CASP5, TLR7, MAP2K5, CD47, ATM, CDC25C, TTK, SRC, PDGFRA, ITGB1, and ITGB3. The gene discussed is MAP2K5; the disease is lymphoma.