This is quite evident in the hippocampus, where the consumption of EtOH in the intermittent model promotes the reduction of neurogenesis, hippocampal volume, synaptic communication, and neurotrophins associated with neuroplasticity as a brain-derived neurotrophic factor (BDNF) [2, 5–8], which is therefore strongly associated with cognitive impairments. Here, BDNF is linked to Cognitive impairment.