Similarly, higher tumor grade (poorly differentiated vs. well/moderately differentiated), later stage, larger size, positive lymph node status, presence of lymphovascular invasion (vs. absence), ER- status (vs. ER+), and more aggressive breast cancer subtypes (namely ER-/PR-/HER2+ and ER-/PR-/HER2- vs. ER+/PR+/HER-) were associated with increased odds of breast cancer self-detection compared to detection through mammography. This evidence concerns the gene ERBB2 and breast cancer.