SLC12A2 and neurodevelopmental disorder: In addition, since GABA action principally depends on the expression of NKCC1 and KCC2 chloride cotransporters, and the disruption of KCC2 expression is associated with a variety of neurodevelopmental disorders including ASD [11, 51–53], we evaluated its expression in the different layers of CA3 in our model at P14-P15.