IFNG and Guillain-Barre syndrome: In other clinical conditions, the presence of anti-cytokine AAbs might correlate with disease resolution; for example, an increase in anti-IL-1 AAbs correlates with milder disease course in rheumatoid arthritis (12), anti-interferon alpha (IFNα) AAbs have been noted to have an inverse correlation with disease severity in SLE (13), and high levels of anti-IFNγ AAbs correlate with resolution of Guillain-Barre Syndrome (16).