As far as we know, this is the first study to investigate the association of these five polymorphisms (rs14035 in RAN, rs11077 in XPO5, rs13078 in DICER1, rs3742330 in DICER1 and rs784567 in TARBP2) with the risk of T2DM and its vascular complications. Here, DICER1 is linked to type 2 diabetes mellitus.