CRP and major depressive disorder: Tables 1A, 1B, and 1C show the data of the systematic review of the 19 selected articles (see the section Search Strategy for Systematic Review) regarding the predictive capability of inflammatory state [assessed by serum/plasma immune compounds (mainly CRP and cytokines) (only one study used CSF)] in patients with MDD for the response rates to various classes of antidepressant drugs and to anti-inflammatory agents added to an antidepressant regimen (except for one study, in which the anti-inflammatory agent was used as monotherapy) (52).