CYP19A1 and breast carcinoma: To determine whether the aromatase promoter mainly active in vascular endothelial (VE) cells in breast cancer, the aromatase-promoter I.7, is involved in the regulation of aromatase expression, we used RT-PCR to amplify the aromatase endothelial-specific promoter I.7 transcripts from RNA extracted from HUVECs.