BCA has been shown to attenuate hypertension in ovariectomized rats by decreasing the systolic, diastolic, and mean arterial blood pressures; decreasing oxidative stress and the tumor necrosis factor-α (TNF-α) levels; and increasing the NO levels in an eNOS-dependent manner (Sachdeva et al., 2016). The gene discussed is TNF; the disease is hypertensive disorder.