MMP2 and lung cancer: BCA could effectively inhibit the proliferation of lung cancer cells by downregulating Ki-67, induce apoptosis by activating the cleavage of caspase-3 and caspase-9, and suppress cell migration by downregulating matrix metallopeptidase-2 (MMP-2) and vascular endothelial growth factor (VEGF) (Lai et al., 2018; Hsu et al., 2018).