DNM2 and Haim-Munk syndrome: Furthermore, overrepresented GO terms based on differentially expressed genes have revealed biological processes and molecular functions that are involved in synaptic plasticity (chemical synaptic transmission and synaptic signaling), cell membrane permeability (ion channels, potassium channel activity, and voltage-gated ion channel activity), and cytoskeleton (cytoskeletal protein binding and actin binding) and may be the key factors in the HMS pathogenesis as well (Table S3).