Synergization with cisplatin, pristimerin led to apoptosis via inhibiting the miR-23a, regulating PTEN/Akt signaling-related PTEN and the phosphorylation of Akt and GSK3β in lung carcinoma NCI-H446 and A549 cells (Zhang et al., 2019). The gene discussed is GSK3B; the disease is lung carcinoma.