FTO and obesity due to melanocortin 4 receptor deficiency: Similarly, Loos et al. emphasized that the C allele of the same gene was associated with an increased risk for developing obesity15, while Garcia-Solis et al. underlined a positive correlation between FTO rs9939609 homozygotes and MC4R rs17782313 heterozygotes and increased risk for both obesity and high blood pressure values in Mexican school-aged children25.