The clinical data and magnetic resonance imaging (MRI) findings of previous reported individuals with RNASET2-deficient leukodystrophy were also reviewed and compared to the findings of our patient.<h4>Results</h4>Brain MRI findings were suggestive of RNASET2-deficient leukoencephalopathy, AGS and CMV infection. This evidence concerns the gene RNASET2 and cytomegalovirus infection.