Similarly, in transwell assays with or without Matrigel, SMMC-7721 cell overexpressing Lnc34a displayed significantly higher migration and invasion abilities compared with control cells while the opposite results were observed in HCC-LM3 cell underexpressing Lnc34a (Fig. 2c and d; Additional file 4: Figure S1C and D). Here, MIR34AHG is linked to hepatocellular carcinoma.