FZD10 and cholangiocarcinoma: Similarly, here, the presence of FZD10 was detected in the exosomes secreted by colon cancer, gastric cancer, hepatocellular carcinoma, and intrahepatic cholangiocellular carcinoma cell lines, which are in total the investigated metastatic cell lines (HGC-27, SW-620, N-87, HUCCT-1 cells), apart from the HLF cells.