FZD10 and neoplasm: Moreover, FZD10 and FZD10-mRNA delivering exosomes can also be thought to be messengers of cellular transformation by transferring of exosomal FZD10-mRNA and to play an active function in long-distance metastatization, as both the pathological protein and, more importantly, its corresponding mRNA, are secreted by the cells involved in the primary tumor constitution through exosomes.