VEGFA and carcinoma: In a series of 148 PitNETs, six of which were carcinomas [22], Lloyd et al. found an increased VEGF expression, by immunohistochemistry, in non-treated somatotroph tumors, silent corticotroph tumors, non-oncocytic null cell tumors, and in carcinomas in comparison to the other subtypes, while VEGF expression was decreased in tumor tissue in comparison to the adjacent non-tumor tissues when the latter was present [22].