However, in contrast to commonly observed positive association between miRNAs and NF-κB in HCC, some cholangiocarcinomas display opposing effects of specific miRNAs (e.g., miRNA-200c, miRNA-141) and NF-κB, in the context of (cancer)stemness and poor prognosis of the patients [121]. The gene discussed is NFKB1; the disease is cancer.