MIF and cancer: Hence, exosomes are released into the blood [125] and may have a varying composition in proteins, mRNA, DNA, etc. The detailed study of these molecules through multi-omic approaches might offer relevant information to cancer progression and angiogenesis (through vascular endothelial growth factor (VEGFR) or fibroblast growth factor (FGF)) [15,125], EMT (vimentin, caveolin-1 or IL-6) [126], metastasis (macrophage migration inhibitory factor (MIF), miR-17-5p) [127,128], and/or drug resistance [129].