Thus, the top two AML genes, MPO (myeloperoxidase) and PML (promyelocytic leukemia) have the GCHs 22.96 and 21.95, below those of the 56th and the 59th ranked ribosomal proteins RPL29 (23.64) and RPL13 (22.12). The gene discussed is PML; the disease is acute promyelocytic leukemia.