According to our results, certain ribosomal genes (RPL13A, RPS5) are more influential in dictating/preserving the HL-60 phenotype than RARA (retinoic acid receptor alpha, GCH = 19.67), the gene whose translocation t (15;17) [54,55] is associated with 98% of acute promyelocytic leukemia cases. This evidence concerns the gene RPS5 and acute promyelocytic leukemia.