EGFR and non-small cell lung carcinoma: In the pre-clinical setting, Amornwichet et al. [14] found that radiosensitivity determined by D10 from clonogenic assays was significantly higher for EGFR mutant cells than for EGFR wild-type cells in a panel of NSCLC cell lines, as well as in genetically engineered isogenic NSCLC cells.