As a redox sensitive kinase, GSK3β activity may be augmented, either through changes in its inhibitory phosphorylation state at serine 9, during the phase of acute injury [36,63], or alternatively via increased expression as seen in chronic diseases, such as diabetes, inflammatory disease and neurodegenerative diseases [[64], [65], [66], [67]]. The gene discussed is GSK3B; the disease is neurodegenerative disease.