FGFR2 and neoplasm: To date, all reported selfish mutations occur in growth factor receptors [fibroblast growth factor receptor 2 and 3 (FGFR2, FGFR3), RET] and members of the RAS/mitogen activated protein kinase (RAS/MAPK) signaling pathway and are identical or allelic to oncogenic mutations identified in tumor samples (Goriely and Wilkie 2012, Maher et al. 2018).