Given the high comorbidity rates of ASD and FXS (40–74% of males and 13–45% of females with FXS meet ASD criteria) [44–49], and overlap in pragmatic language profiles in particular [34, 47–50], it is possible that the FMR1 gene might play some role in the development of ASD traits, and the language-related phenotypes of those with ASD in particular. Here, FMR1 is linked to fragile X syndrome.