Furthermore, both univariate (HR = 0.371, 95%CI: 0.269–0.513, P < .001) and multivariate (HR = 0.485, 95%CI: 0.297–0.793, P = .004) Cox regression analyses suggested that low expression of SLC16A12 mRNA was an independent prognostic factor for patients with ccRCC. Here, SLC16A12 is linked to nonpapillary renal cell carcinoma.