One study reported an association between the maternal EPHX1 rs1051740 polymorphism and the risk of craniofacial abnormalities in offspring.[23] Another study in 2012 showed that the maternal EPHX1 rs1051740 genotype was associated with increased risks for childhood medulloblastoma.[27] In the present study, we found that pregnant women with the EPHX1 rs1051740 polymorphism conferred the risk of right-sided obstructive malformations before FDR correction. Here, EPHX1 is linked to medulloblastoma.