An inflammatory and oxidative status was also demonstrated in the serum of RA patients, including over‐expression of IL‐6, IL‐8, IL‐17, MCP‐1, TNF‐α, IFN‐γ, sP‐selectin and VEGF (Figure 1F), increased levels of LPO (Figure 1G) and reduced TAC (Figure 1I). This evidence concerns the gene IFNG and rheumatoid arthritis.