Similarly, during healing at the tenth day; the ulcer swabs showed statistically significantly higher mean endocan and VEGF levels 1.9 ± (1.1) and 788.5 ± (152.0) pg/ml respectively than those of the healthy mucosal site 1.1 ± (0.5) and 518.6± (61.7) pg/ml respectively P-value = 0.009 and < 0.001, respectively ( Table 2). The gene discussed is VEGFA; the disease is ulcer disease.