This evident association linking VEGF to the ulcerative process identified in our study is consistent with former studies associating the levels of VEGF with oral aphthous ulceration and with proof from other ulcer-related disorders as Behçet Disease where clinical proof advocates that VEGF could be directly involved in oral ulcers formation in Behçet Disease (11,14,37,38). Here, VEGFA is linked to Oral ulcer.