BRCA2 and endometrial carcinoma: Interestingly, the one patient with non-HBOC phenotype (endometrial carcinoma) had a complex family history of maternal HBOC history (breast and ovarian cancers) with pathogenic 6794 insA variant in BRCA2 and paternal Lynch syndrome history (colon, lung and bone cancers) without any familial variant reported [28].