According to the enrichment results, the hub nodes of the network for miR-29a targets were significantly enriched into several important pathways including pathways in cancer, focal adhesion, PI3K-Akt signaling pathway, microRNAs in cancer, colorectal cancer and proteoglycans in cancer while the hub nodes of the network for miR-29b targets were linked with pathways in cancer, proteoglycans in cancer, HIF-1 signaling pathway, PI3K-Akt signaling pathway, microRNAs in cancer, colorectal cancer and VEGF signaling pathway. This evidence concerns the gene AKT1 and cancer.