However, in D-bLP + laser-treated tumor, these signals were remarkably weakened, and the mean optical density (MOD) value was drastically decreased by 95.4% for α-SMA, 81.9% for CD31, and 81.3% for F4/80 in comparison with the untreated control tumors (Fig. 4a, e). Here, ACTA1 is linked to neoplasm.