TSC22D3 and post-traumatic stress disorder: To assess causality between reduced amygdala GILZ levels and the increased susceptibility to PTSD-like behavior, we mimicked the stress-induced GILZ downregulation with KD GILZ levels using short hairpin (sh) RNA expressing lentiviruses, delivered specifically and bilaterally to the basolateral amygdala (BLA) of adult naïve mice.