CRH and viral infectious disease: In a separate cohort of dams, we confirmed the induction of CRF in the choroid plexus cells, immunohistochemistry staining for CRF (red) and GFP (viral infection marker, green) in maternal brains with or without Dox induction was performed on brains removed on day E17.5, 4 days after Dox administration (Fig. 2b).