In order to elucidate the impact of each of the two stressors, CRF-inducedPNS and PTSD induction, independently or in combination, on amygdalar GILZ, FKBP51, GR, and CRF, three-way ANOVA analyses were performed between the following factors: “CRF-inducedPNS” (Control/ CRF-inducedPNS), “PTSD-induction” (No PTSD induction/‘Adulthood PTSD induction’); With-in factor with repeated measures: ‘amygdala levels’ (GILZ/FKBP51/GR/CRF). The gene discussed is FKBP5; the disease is post-traumatic stress disorder.