Preliminary results from two PARPi and PD-1/PD-L1 blockade combination trials were presented showing early clinical activity in subsets of recurrent ovarian cancer; 25% RR of niraparib and pembrolizumab in platinum-resistant ovarian cancer [17] and 72% RR of durvalumab and olaparib in germline BRCA mutant platinum-sensitive ovarian cancer patients [18]. This evidence concerns the gene CD274 and ovarian cancer.