Ten variables, including age, alcohol drinking, cigarette smoking, diabetes mellitus, coronary artery lesions, ALDH2 genotype and medications (clopidogrel, statins, ACEI/ARB, and nitrite) were selected for univariate regression, and the results showed that patients with type 2 diabetes (OR = 1.647, 95% CI: 1.029–2.611, p = 0.035), carriers of the ALDH2*2 allele (OR = 1.537, 95% CI: 1.005–2.339, p = 0.046) and those who use of the antiplatelet medication clopidogrel (OR = 1.697, 95% CI: 1.018–2.934, p = 0.049) were at an increased risk for ISR (Table 2). Here, ALDH2 is linked to diabetes mellitus.