In a multivariate analysis, the odds ratios for CAD and PAD were 0.65 (95% CI: 0.42–0.99, p < 0.05) and 2.12 (95% CI: 1.03–4.37, p < 0.05) for low HO-1 level (<0.35 ng/mL), respectively. Here, HMOX1 is linked to peripheral arterial disease.