Also, compared to WT mice, lower levels of liver markers (AST, ALT, Bil), cytokines (Tnfα, Tgfβ, Il6), and tumor markers (c-Myc, Mmp2, Epcam) in Pecam-1-deficient mice after TAA-application underline the important functions of PECAM-1. The gene discussed is GPT; the disease is neoplasm.