NUPR1 and infectious disease: Although our study was exploratory, it did result in novel findings: 1) We report for the first time that NUPR1 is expressed at the site of infectious disease; and, 2) We provide novel information about the mechanism of NUPR1 induction, demonstrating that it is induced by a human pathogen via the production of type I IFN and giving new insight into the link between NUPR1 and microbial infection.